Friday, 4 September 2015

Intraoperative Bronchospasm

this topic was given recently as 'what are the differential diagnosis of intraoperative Bronchospasm and what is its management?"



 The differential diagnosis of intraoperative bronchospasm are
preexisting Bronchospastic Disease
asthma
Chronic obstructive pulmonary disease
Bronchopulmonary dysplasia
Bronchospasm Induced Under Anesthesia
Tracheal intubation
Surgical stimulation under light plane of anesthesia
Hypersensitivity reactions (histaminoid, anaphylactoid or anaphylactic)
Aspiration of gastric contents
Mainstem bronchial intubation or carinal irritation by endotracheal tube
Pulmonary edema (cardiogenic or negative pressure)
Conditions Mimicking Bronchospasm (increased peak inspiratory pressure, decreased tidal volume, wheezing)
Kinked tracheal tube or breathing system
Secretions
Obstruction of the tube by overinflated or herniated cuff
Pneumothorax (simple or tension)

What Therapeutic Approaches Are Used to Prevent Bronchospasm?
▪ PREVENTION
Preoperative identification of patients who are likely to develop perioperative bronchospasm helps to optimize the medical condition
▪ TIMING OF ELECTIVE SURGERY
Smoking cessation is the  most effective  way for most people to reduce the risk of  perioperative pulmonary complications.
 The surgical site is the most important predictor,Upper abdominal and thoracic surgery represents the greatest risk.
Elective surgery scheduled 6-8 weeks post cessation of smoking
Eradication of infection,physiotherapy to enhance drainage of sputum.
Start on steroids and bronchodilators 3-5days in advance
Option of regional anesthesia whereever possible
Minimal stimulation of airway
Anxiolytics and antihistaminics prior to surgery

Diagnosis of intraopearative Bronchospasm
Wheeze,increase in peak inflation pressure,decreasing exhaled tidal volume,slow rising capnogragh

Therapeutic Approach to Intraoperative Bronchospasm
1) Rule out mechanical causes for wheezing such as tube obstruction, mainstem bronchial intubation, pneumothorax
2) Deepen the anesthetic using volatile or IV anesthetics, 
3) stop surgical stimulation
4) Nebulized β2 agonists (albuterol) up to 10 puffs and steroids
IV lidocaine 1.5 mg/kg,
5) Adjust the ventilator settings to achieve adequate oxygenation, yet minimize the peak and mean inflation pressures
6) Consider neuromuscular blockade
7) Intravenous corticosteroids, hydrocortisone 2-4 mg/kg
8) Consider deep extubation, postoperative ventilatory support



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